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Future research should explore immune-modulatory interventions, such as leveraging the JAK/STAT pathway for neuroprotection and enhancing innate and adaptive immune clearance of toxic aggregates [176,177]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 106.Maier-Begandt D, Comstra HS, Molina SA, Krüger N, Ruddiman CA, Chen Y-L, Chen X, Biwer LA, Johnstone SR, Lohman AW, Good ME, DeLalio LJ, Hong K, Bacon HM, Yan Z, Sonkusare SK, Koval M, Isakson BE